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Deadlier Opioid Analogue Surfaces in San Francisco
15 Sep
Summary
- New 'cychlorphine' drug is possibly ten times stronger than fentanyl.
- Counterfeit pills containing cychlorphine mimic common pharmaceuticals.
- California has not yet classified cychlorphine as an illegal drug.

San Francisco is confronting a new public health challenge with the emergence of cychlorphine, a dangerous opioid analogue that police warn could be ten times stronger than fentanyl. The drug has been found in counterfeit pills designed to resemble legitimate pharmaceuticals such as Xanax, Adderall, and OxyContin. This poses a significant risk, as these counterfeit medications are pressed with "poisonous chemicals" by dealers and can bypass standard drug test strips.
Last week, San Francisco police announced the arrest of four individuals suspected of dealing cychlorphine and other narcotics, following an investigation into the fatal overdose of a 16-year-old earlier this year. Cychlorphine was detected in the teenager's system. Naloxone, the opioid overdose reversal medication, may be effective, but its efficacy is uncertain given the drug's potency and rapid effects.
The Drug Enforcement Administration has placed cychlorphine under a temporary Schedule 1 narcotic status, but it is not yet a classified illegal drug in California. This legal gap makes prosecution difficult. City officials, including District Attorney Brooke Jenkins and Mayor Daniel Lurie, are calling for immediate legislative action to make possession and distribution of cychlorphine illegal at the state level, aiming to prevent a repeat of the challenges faced during the fentanyl crisis.