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Joe Manganiello's Near-Death Health Ordeal Revealed
23 Jun
Summary
- Manganiello faced a cascade of autoimmune illnesses attacking multiple body systems.
- A seven-year battle included chronic pain and life-saving organ amputation.
- The actor's memoir explores his health crisis, ancestry, and inherited trauma.

Joe Manganiello is set to publish his memoir, Bloodlines, on October 16, detailing a severe, undisclosed health crisis. The book chronicles a seven-year period where Manganiello experienced a sudden onset of autoimmune illnesses that impacted his skin, thyroid, eyes, lungs, and digestive system.
This prolonged health battle was marked by chronic pain and culminated in a life-saving organ amputation. Manganiello described this time as the most challenging of his life, yet also his greatest adventure.
Beyond his personal health journey, Bloodlines will explore themes of inheritance, masculinity, faith, ambition, and identity. The memoir also delves into a quest for answers about his ancestry and inherited trauma, offering readers hope for healing.