How did Drena De Niro's son, Leandro, die?

Leandro De Niro Rodriguez died in July 2023 from an accidental overdose involving fentanyl and other substances.

What role did online activity play in Leandro De Niro Rodriguez's death?

Drena De Niro believes that her son's involvement with online activities and exposure to illicit substances played a role in his death.

What is the Leandro De Niro Rodriguez Foundation?

The foundation, established by Drena and Robert De Niro, aims to expand access to care for young people and families impacted by the fentanyl crisis.

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De Niro's Grandson: Online Dangers Led to Fatal Overdose

29 Nov, 2025

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Summary

Leandro De Niro Rodriguez died from an accidental fentanyl overdose.
His mother believes online activity contributed to his death.
A foundation was established in his name to combat the fentanyl crisis.

De Niro's Grandson: Online Dangers Led to Fatal Overdose

Drena De Niro, daughter of Robert De Niro, shared her perspective on the accidental fentanyl overdose that claimed her only son, Leandro De Niro Rodriguez, at 19. She revealed that Leandro's online activity, alongside exposure to potent drugs like fentanyl, contributed to his rapid decline.

Rodriguez's death in July 2023 was officially ruled an overdose due to multiple substances, including fentanyl. Drena expressed her grief and frustration, particularly concerning individuals who sold laced pills. She noted that Leandro had been seeking help and had discussed rehab prior to his passing.

In response to this profound loss, Drena and Robert De Niro launched the Leandro De Niro Rodriguez Foundation. This organization aims to increase access to care for youth and families affected by the fentanyl crisis, striving to prevent other families from enduring similar pain.